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Addison's, AKA hypoadrenocorticism, is a very well recognised condition of the adrenal glands, and affected individuals require supplemental mineralocorticoid therapy to maintain normal serum electrolyte concentrations. Addison’s disease occurs when the adrenal cortex is damaged and the adrenal glands do not produce enough steroid hormones called cortisol and aldosterone. Cortisol regulates the body’s reaction to stressful situations. Aldosterone helps with sodium and potassium regulation. Additionally, the adrenal cortex produces sex hormones (androgen).  Addison's disease can occur as a primary immune destruction of the adrenal cortex, or as a secondary problem due to failure of the hypothalamic/pituitary control centers to adequately regulate adrenal function. Hypoaldosteronism (aldosterone is the main mineralocorticoid hormone) may also occur as a consequence of kidney disease, or liquorice toxicity.

This  Addison´s Disease Prevention and/or Curing Protocol is for people who are ready to take the full responsibility for their own health.

"The person who says it cannot be done should not interrupt the person doing it."
Chinese Proverb.

The protocol incorporates lifestyle change, and implements healthy diet, body cleansing, exercises and different traditional and natural therapies. Protocol contains links to other pages that give detail explanation for each part of this program. Please, follow the links, to fully understand all the words. Remember: There is always something that can be done! The first thing to do is to change your mood. If you are depressed, if you are unhappy, you can not be healthy. Advice: start with the Laughing cure!

Laughing provides us with the natural inner massage, and through change of mood it can account for up to 30% of cure!

Foods that Cause or worsen Addison's disease:
  1. Alcohol and caffeine (soda, chocolate (refined), coffee, cocoa, etc.)
  2. Contaminated foods (E.Coli and other harmful bacteria from poor food handling)
  3. Chemicals found in processed and fermented foods (dyes and preservatives) wine, vinegar, soy sauce, tofu, etc.)
  4. A diet high in refined sugars and other carbohydrates (candy, cookies, sodas, processed foods, white bread, etc.)
  5. Foods contaminated by parasites (pork, chicken, fish)
  6. Antibiotic use (interferes with your bodies natural flora and antibodies)
  7. Ingestion of animal products that have been given hormonal and antibiotic treatments (either through injections, water or feed).
  8. NSAID's (non-steroidal anti-inflammatory drugs). 

Found above the kidneys, adrenal glands produce the hormone cortisol that helps the body:
  • Counter stress
  • Regulate carbohydrate, protein, and fat metabolism
  • Reduce the inflammatory response of the immune system
  • Sustain cardiovascular function
  • Keep optimal blood pressure levels
  • Balance insulin
  • Maintain feelings of comfort
The aldosterone hormone is also fashioned in the adrenal glands as it helps balance water and salt as well as helps to steady blood pressure. Without proper levels of aldosterone, kidneys cease proper functioning causing a reduction in blood pressure and volume.

Addisons disease can affect anyone at any age, but is most common in middle-aged adults. Aside from the above-mentioned symptoms, people with Addisons disease may experience:
  • Salt cravings
  • Depression
  • Nausea (including vomiting and diarrhea)
  • Pain in joints
  • Pain in muscles
  • Hypoglycemia (low blood sugar) 
A sudden onset of Addisons disease is known as addisonian crisis and is the cause of acute adrenal failure. In these cases, patients may experience:
  • Dehydration (caused by diarrhea and vomiting)
  • Lower back pain
  • Abdominal pain
  • Pain in legs
  • Low blood pressure
  • Higher than normal potassium levels
  • Fainting 
Autoimmune diseases are the most common contributors to adrenal failure as the body suspects the adrenal cortex as a threat it seeks to destroy. Tuberculosis, cancer of the adrenals, surgical adrenal gland removal, bleeding, and other infections in the adrenal glands also contribute to adrenal failure.

Patients being treated for arthritis or asthma who suddenly stop taking prescribed corticosteroids sometimes suffer secondary adrenal insufficiency. And those who consume large amounts of coffee and other caffeinated foods over a period of years are prone to adrenal exhaustion that can leave the adrenal glands in a weakened, more susceptible state. While the daily consumption of one or two cups of coffee aren’t likely to cause immediate harm, regular caffeine consumers are advised to keep daily consumption to a minimum and, whenever possible, take a break from consumption in order to give the adrenal glands time to rest.

Left untreated, Addisons disease can result in addisonian crisis if triggered by stress, illness, infection or injury.

In order to treat Addisons disease, doctors seek to substitute cortisol or aldosterone, according to which one is not being properly produced. In the case of aldosterone substitution, or replacement, patients are also encouraged to increase salt consumption. In more chronic cases, surgery is often prescribed. Also, if a patient is in addisonian crisis, intravenous doses of saline, dextrose and hydrocortisone are administered, as low levels of these are life threatening. 

Physicians in China may prescribe Liquorice alone or with cortisol to treat mild cases of Addison's disease, in which the body produces too little of this hormone. 

Alternative therapies for those already living with Addisons disease include herbal blends such as Huang Qi, Borago, and Siberian ginseng, which help to balance the effects of stress as well as help maintain the optimal functioning of the adrenal glands. Ginger also helps in digestion and can help alleviate nausea, including vomiting. Acupuncture, Yoga, prayer, and meditation also help to reduce stress levels that can be threatening to the adrenals and which lower the immune system in general.


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Looking for Answers
Despite its prevalence, the level of basic autoimmune research funding is below 3% of the National Institutes of Health (NIH) total budget, which may explain why we understand so little about the roots of these diseases.  The whole arena of autoimmune research is in its infancy. Though there are many theories about the origins of autoimmune diseases—such as the hygiene hypothesis theory, which suggests that the rise of such diseases in industrialized nations may be linked to cleanliness, vaccines, and decreased exposure to bacteria—scientists don’t fully understand why the immune system is unable to recognize its own cells or regulate its response. We do know there are factors at the root of autoimmune disease development, which include both genetic and environmental components.

Currently, researchers are beginning to understand that autoimmunity may play an important role in many chronic conditions, such as cardiovascular disease. In fact, the NIH established the Autoimmunity Centers of Excellence to promote research in areas such as lupus, multiple sclerosis, pemphigus vulgaris, rheumatoid arthritis, scleroderma, and Sjögren’s syndrome. The goal is to foster collaborative research across scientific disciplines and medical specialties to find effective treatments and prevention approaches.

Role of Inflammation
A hot topic on the autoimmune disease front is the role that chronic inflammation—present in many autoimmune diseases—plays in its development. In rheumatoid arthritis, the damage to tissues is caused by an inflammatory reaction to the presence of antigens. Which brings to mind the old “chicken and the egg” question: Which comes first, inflammation or autoimmunity? “In rheumatoid arthritis, is it caused by inflammation and autoimmune disease comes secondarily, or is it caused by autoimmunity? The evidence is unclear,” says Noel R. Rose, MD, PhD, a professor of molecular microbiology and immunology and director of the Johns Hopkins Autoimmune Disease Research Center.

The Autoimmune Disease Specialty
Your clients may be hard-pressed to find a dietitian—or even a doctor, for that matter—specializing in autoimmune disease. AARDA reports that modern medicine is organized on the basis of the anatomy of disease or in what part of the body disease occurs. There’s no specialty that focuses on autoimmunity; instead, an autoimmune disease is treated by the medical specialty that covers the particular anatomical part involved. Thus, dermatologists typically treat dermatological autoimmune diseases and gastroenterologists treat inflammatory bowel disease. But autoimmune diseases aren’t always neat and precisely limited to one body part or system—crossovers occur all the time.

It’s been established that if you have one autoimmune disease, you’re at higher risk for developing others. For example, in celiac disease, which is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains in genetically susceptible persons, the comorbidity between other autoimmune diseases has been documented. “There’s a correlation between celiac disease and other autoimmune diseases, such as type 1 diabetes, autoimmune thyroid disease, Sjögren’s syndrome, autoimmune liver disease, inflammatory bowel disease, and Addison’s disease,” says Shelley Case, RD, a celiac disease diet expert and author of Gluten-Free Diet: A Comprehensive Resource Guide. “For example, the prevalence of celiac disease in type 1 diabetes is between 5% and 15%,” she says.

Nutritional Management
It’s important to consider nutritional red flags that may arise during the management of autoimmune conditions. Typical drugs used in treatment, such as analgesics and nonsteroidal anti-inflammatory drugs, corticosteroids, disease-modifying drugs, and biologic response modifiers, may cause side effects such as nausea and vomiting, stomach pains, mouth sores, and decreased appetite. And some drugs can interact with specific nutrients, such as folic acid and vitamin B12. In addition, alterations in energy and protein metabolism that lead to muscle loss and wasting may occur in some autoimmune diseases.

The nutritional management of autoimmune diseases usually emphasizes controlling pain and inflammation, slowing the progression of the disease, and boosting the immune system. And a few promising foods and nutrients are emerging as potentially beneficial.

Let in the Sunshine Vitamin
Perhaps the most intriguing area of nutrition research involves vitamin D. For decades, researchers have noticed a relationship between sunlight exposure and vitamin D intake and autoimmune disease risk. “Some studies have found that people with autoimmune diseases such as multiple sclerosis are more likely to have lower levels of vitamin D than other people,” Rose says. “Many autoimmune diseases are more common if you live further from the equator. This is true for both multiple sclerosis and type 1 diabetes and probably for lupus.”

Many studies have explored the association between vitamin D and autoimmune disease. A November 2001 study published in The Lancet that followed participants for 30 years revealed that children born in Finland in 1966 who received supplemental vitamin D during the first year of life had a significantly lower risk for developing type 1 diabetes, while children with vitamin D deficiency during the first year of life had a significantly higher risk for developing type 1 diabetes. The Iowa Women’s Health Study found a lower risk of rheumatoid arthritis associated with higher vitamin D intake, according to the January 2004 issue of Arthritis & Rheumatism.

Several studies suggest that vitamin D may lower the risk of developing multiple sclerosis, as well as lessen the frequency and severity of symptoms. According to Michael Holick, PhD, MD, director of the Vitamin D, Skin, and Bone Research Laboratory at Boston University School of Medicine, if you’re born below 35˚ latitude, located approximately at Atlanta and live at this latitude for the first 10 years of your life, you have a 50% reduced risk of developing multiple sclerosis. In addition, he reports that women and men who increase their vitamin D intake to more than 400 IUs per day reduce the risk of developing multiple sclerosis by approximately 40%. The Nurse’s Health Study also found a protective relationship between vitamin D supplements and multiple sclerosis risk, as was reported in Neurology in January 2004. And in a new study published in September in Neuroepidemiology, data from participants enrolled in the Multiple Sclerosis Surveillance Registry suggested that exposure to vitamin D before multiple sclerosis onset may slow disease-related neurodegeneration and delay progression to disability.

How does vitamin D work in the immune system? In the 1970s, researchers discovered vitamin D receptors in many of the body’s cells, including islet cells of the pancreas, lymphocytes, and colon enterocytes. This led to the revelation that vitamin D helps keep the immune system functioning properly by inhibiting the proliferation of T cells and decreasing the production of proinflammatory cytokines.

“Vitamin D deficiency may be more common in this country than we assumed,” Rose says. “There seems to be suggestive evidence on the role of vitamin D, but we have much to learn. There are no clinical studies yet showing that giving large doses of vitamin D benefits autoimmune disease. The level that we need to prevent disease and maintain health may not be the same.”

The Microbiome and Autoimmunity
An up-and-coming area of human health research focuses on the impact of balancing the gut microbiota. Disruption of the intestinal ecosystem equilibrium has been linked with many diseases, including autoimmune disorders; thus prebiotics and probiotics have been called the “next frontier” in therapeutics by health researchers. Animal and some human studies have shown that probiotic cultures can enhance levels of immunoreactive cells, regulate immune factors, modulate immune dysregulation, and promote gut barrier function and anti-inflammatory responses.



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Kombucha and water kefir have about 1000 times the amount of probiotics as a cup of yogurt.

Recently, the effects of probiotics on various autoimmune disorders have been investigated. Scientists are exploring how the microbiome (microbes, their genetic elements, and environmental interactions) may be different in children with type 1 diabetes compared with healthy children. In a January 2010 pilot study published in BMC Complementary and Alternative Medicine, a probiotic treatment resulted in improvement in pain and self-assessed disability in 45 adults with rheumatoid arthritis. And in a June 2006 review published inPostgraduate Medical Journal, Chinese researchers reported that preliminary studies suggest probiotics may be of benefit for colitis and inflammatory bowel disease because they may balance aberrant enteric microflora and reinforce the intestinal defense system.

Gluten Autoimmune Triggers
When it comes to celiac disease, the treatment is simple: Follow a gluten-free diet for life. “Other autoimmune diseases have no proven cause or cure, but we know that three factors play a major role in the development of celiac disease: Specific genetic markers HLA DQ2 and DQ8, consuming gluten, and certain environmental factors,” Case says. Recent studies have revealed that the bacterial composition of the gut may be one of the possible environmental factors behind celiac disease. Although more research is needed, we do know that if individuals are diagnosed early and follow a healthful gluten-free diet, the risk for complications such as osteoporosis, gastrointestinal cancer, and the development of other autoimmune diseases can be greatly reduced.

Today, going gluten free is a popular treatment for many other autoimmune diseases outside of celiac disease, including lupus, multiple sclerosis, and rheumatoid arthritis. But is there proof that this approach works? “There’s no evidence that gluten-free diets will help all autoimmune diseases. But I do believe that many people with certain autoimmune diseases may have undiagnosed celiac disease. Should you tell everyone to follow a gluten-free diet? No. First, they should get tested if they have symptoms of a gluten sensitivity because if someone already is on a gluten-free diet, the celiac tests can be falsely negative,” Case says.

Power of Omega-3 Fatty Acids
The potential benefits of omega-3 fatty acids in autoimmune disease also have attracted the attention of researchers. Omega-3 fatty acids —EPA and DHA—possess potent immunomodulatory activities.  The anti-inflammatory properties might make them useful in the management of autoimmune diseases; thus they’ve been investigated in conditions such as arthritis, Crohn’s disease, lupus erythematosus, multiple sclerosis, and rheumatoid arthritis—the latter being one of the most widely studied areas. 

Anti-Inflammatory Eating 
One approach dietitians can support is an anti-inflammatory, antioxidant eating strategy aimed at decreasing inflammation and oxidative stress and promoting a healthy immune balance. We know that inflammation goes hand in hand with autoimmune disease, but don’t underestimate the significance of oxidative stress. During an immune response, there’s an increase in the production of free radicals, which can result in oxidative stress—a process marked by a negative shift in the natural balance between pro-oxidants and antioxidants that results in biological damage. In fact, much of the damage in autoimmune disease can be linked to free radical damage to cell membranes and tissues. Studies have documented that oxidative stress and low antioxidant activity occur in autoimmune disease. The antioxidant vitamin E is deficient in 50% to 60% of patients with rheumatoid arthritis. And in a February study published in theBosnian Journal of Basic Medical Sciences, multiple sclerosis patients were found to have a significantly lower antioxidant capacity compared with control subjects. While not many studies have examined the effects of eating a diet rich in anti-inflammatory, antioxidant foods and nutrients, most experts believe this approach is worth trying.

“Antioxidants play a role in autoimmune disease. Celiac disease is an inflammatory disease. We’re finding that long after people are diagnosed and are following a gluten-free diet, their guts aren’t healed yet. It can’t hurt for people to eat more antioxidant-rich fruits and vegetables,” Case says.

Donna Sigmond, MS, RD, a Colorado-based dietitian specializing in autoimmune diseases, enthusiastically recommends an anti-inflammatory diet to her patients. “I encourage green leafy veggies and other foods that can reduce inflammation, such as high-fat veggies like avocado and walnuts to provide high omega 3 levels.  Seed oil from flax also can be beneficial. The focus should be to identify and eliminate inflammatory foods and nourish with real foods that deliver vitamins, minerals, and antioxidants,” Sigmond says.

In a study published August 15, 2006, in the Journal of the American College of Cardiology, researchers found that diets high in refined starches, sugar, saturated fats, and trans fats and low in fruits, vegetables, whole grains, and omega-3 fatty acids appeared to turn on the inflammatory response. However, a diet rich in whole foods, including healthful carbohydrates, fats, and protein sources, cooled it down. There’s no harm in supporting a diet—optimal for just about everyone—that’s rich in whole plant foods, such as fruits, vegetables, whole grains (quinoa and amaranth), legumes (lentils, chickpeas), nuts, and seeds (pumpkin and sunflower); is rich in healthful fat sources such as extra-virgin olive oil, avocado, nuts (walnuts), and fish; and includes foods such as tea, dark chocolate (cacao), spices and herbs, and red wine in moderation.

Cilantro is also very helpful with autoimmune disorders such as Fibromyalgia, Addison’s Disease, Guillain-Barre syndrome, IBS, Multiple Sclerosis, and Chronic Fatigue Syndrome.


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